The experience of developed countries proved that a country can only get full advantage of an international economic integration zone after deepening its internal integration. This paper analysis the equal-share relationship across regions in Romania (whether there is conformity – pair-wise – between rankings of the output and factor shares), presents some considerations about the direction of spatial distribution of economic activity and measures the internal economic integration between the Romanian regions at both NUT 2 and NUT 3 levels. The results have shown that the distribution of output and factor shares across regions in Romania conforms to a rank-share distribution and that the level of economic integration between the regions is gradually increasing, although differences in economic activity growth and factor distribution.