In the article the author describes the main tendencies of the development of the system of communication routes of Northern Bukovyna and Khotyn region in 1918 – 1940. In the interwar period, in addition to the improvement of traditional modes of transport, new ones were launched. A major impediment to the improvement of transport infrastructure was the devastation during the World War I. During 1918 – 1940 the damaged sections of rails, bridges and stations had to be rebuilt. Similar were the problems with highways, the condition of which was one of the worst in Romania. The progressive shifts should include the establishment of a permanent domestic and international air connection between Northern Bukovyna and Khotyn. Urban public transport has also undergone qualitative changes in the interwar period. There were regular bus routes between the main settlements of the region.