The proceedings of the 2nd International Scientific and Practical Conference "Animal welfare in the conditions of global climate change" (AWCGCC), which took place in Dnipro, April 21-22, 2021, are published in the collection. The information on the current problems in the following areas of research is given: Current issues of ecology and environmental protection; Mechanisms of living organisms adaptation to extreme conditions; Adaptive technologies and strategies under the global climate changes. The problems of environmental science, agricultural science and veterinary science are presented, modern ways of their solution are offered. The collection of materials will be useful for specialists in the field of ecology, biology, agriculture and veterinary medicine, as well as for applicants for educational degrees of Master and PhD.